Concerns were also raised about differences between groups in the average time on the current diet. Questions were raised as to whether three months on a given diet is a sufficient duration to impact cardiac/DCM outcomes, and whether diet history prior to a subject’s current diet may impact the study outcomes.Reporting errors were noted, including errors in Tables 1 and 2, for which the authors requested a correction, and other issues raised to the journal that may impact categorization of some included foods as traditional versus non-traditional.Questions were raised about the statistical analyses reported in the article.The authors have requested a correction to clarify that this was an intentional exclusion, and they have noted that this aspect of the study design aligned with how soy products are being handled in a related FDA investigation. Soybeans are in the legume family, but soybeans and soy products were not considered as legumes for the purpose of categorizing diets in this study.Concerns were raised about potential confounds in the study, for example due to the inclusion of adult, puppy, and prescription-only foods, and due to inclusion of raw and kibble diets in the non-traditional group whereas the traditional group only included kibble.Questions were raised around the criteria used to categorize diets, including about the rationale of including global company sales details in these criteria given the objectives of the study.The authors noted that some of these issues were discussed during pre-publication peer review and/or in the published article. This does not alter our adherence to PLOS ONE policies on sharing data and materials.Ĭoncerns raised about the study are outlined below. There are no patents, products in development or marketed products to declare. Collectively, this did not influence the collection or interpretation of results in this study. Since the time of article submission, JAS has received research support from Nature’s Variety Inc. AJF has a contract with the FDA on unrelated research. The Veterinary Medical Teaching Hospital at UCD received funding from Royal Canin to support a resident, and from Nestlé Purina PetCare to partially support a nutrition technician. A resident on the Nutrition Service, mentored in part by AJF, received funds from the Hill’s Pet Nutrition Resident Clinical Study Grants program, matched by the Center for Companion Animal Health, School of Veterinary Medicine at UCD. AJF received funding from Nutro for graduate student training. AJF received remuneration for lectures or as an advisor on behalf of Nestlé Purina PetCare, Mars Petcare, Synergy Food Ingredients, the Mark Morris and Pet Food Institutes. In response to the concerns about declaration of potential competing interests, the authors have provided the following update to the Competing Interests statement:ĪJF is the Scientific Director and JY is the Technical Director of the Amino Acid Laboratory at the University of California, Davis (UCD) that provides amino acid analysis on a fee for service basis. After this article was published, concerns were raised about undeclared competing interests, and about the study design and conclusions.
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Winter performed often with blues and rock singer Janis Joplin and the two became close during the 1960s.Īmong the blues classics that Winter played during that era were “Rollin’ and Tumblin’,” “Bad Luck and Trouble” and “Good Morning, Little Schoolgirl.” He also teamed up with his brother Edgar for their 1976 live album “Together.” Winters paid homage to Waters on “Tribute to Muddy,” a song from his 1969 release “The Progressive Blues Experiment.” He continued to pick up accolades, producing three Grammy Award-winning albums for Waters and recording with John Lee Hooker, which helped revive their careers. This helped secure a substantial recording contract from Columbia Records in 1969 that led to an appearance at the Woodstock Festival and gave him a wide following among college students and young blues fans.Ĭrowds were dazzled by the speed - and volume - of his guitar playing, which had its roots in urban blues but incorporated elements of rock ‘in roll. 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This puts it ahead of even Total War: Warhammer, which sold 500,000 units after three days. Three Kingdoms, which is the first game in the series to be set in China, sold more than one million units in its first week. Legendary heroes also get unique abilities and can't be killed in battle, though they can be executed if they're captured.Total War: Three Kingdoms is the fastest selling game in the history of Creative Assembly's long-running strategy franchise. Most of what you'll be doing in a battle is moving them around, directing them to hotspots and terrifying mere mortals with devastating charges and special attacks. Some classes are better at fighting other heroes, while others are best used with archers, but all of them can easily hold their own against several units at once. While typical historical Total War generals are just strong cavalry units with the occasional special ability, Three Kingdoms' heroes are super-charged warriors who can smash into units, lock them down and, pretty swiftly, wipe them out. Characters serve so many functions-they could be a general, a minister and overseeing one of your provinces all at the same time-and have all these relationships that it can be tempting to keep them out of harm's way, but they are more than capable of handling themselves. The heroic characters who join your empire are vital to the conquest of China, but that doesn't mean you should hide them behind a wall of spears. You'll probably start to get sick of all the leaders hitting you up for new toys, however, so it's a double-edged sword. It might be the difference between getting told to piss off and making peace. It's amazing what a small wooden pig can get you in return. Another might, however, so you can use any of these things to sweeten the deal when you're at the negotiating table. As you recruit more characters, you'll be able to arm them, give them retainers and put them on a lovely horse, but you'll inevitably end up with a pile of things you don't really need. You'll collect all sorts of personal items and followers, so many that you won't know what to do with them all. It’s a whole lot of hassle that you don’t want to get into. If you want it back, you'll need to declare war on the faction or make a trade. Aside from their name, the random rebellions are treated as entirely separate from the faction, so you can be at peace with the Yellow Turban Rebellion and still fight rebels, but that changes moments the siege ends in their favour. In Three Kingdoms, that settlement immediately joins the Yellow Turban Rebellion. 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Even now, according to reporting based on data from the Organization for Economic Cooperation and Development, Lunden writes, full-time workers in the United States “are guaranteed just ten holidays, a paltry sum when compared to the combined holidays and vacations adding up to thirty-six to thirty-seven days a year for workers in France, Spain, and the United Kingdom.” According to the U.S. By 1900, the lightbulb allowed for round-the-clock work, and work became the measure of an individual’s value. This edition features a user-friendly outline format that helps break down information visually for better comprehension of the material. And in the workplace, the demands for corporate output and profits keep Americans on the job for long hours. Mosby’s Comprehensive Review for Veterinary Technicians, 5th Edition is the ideal review tool which reflects the most recent changes to the Veterinary Technician National Exam (VTNE). Beyond that, she writes, “today, we have carpet laced with benzene and particleboard furniture off-gassing formaldehyde,” both known carcinogens. We live with the legacy of lead-based paint and arsenic in wallpaper. Lunden provides, among other insights, a detailed and absorbing tale of the ill effects of chemicals in our lives. The accumulation of corporate failings outlined in the book - and their effects on our health and health care - is compelling. The Pulitzer judges awarded prizes in the categories of. In the telling, “American Breakdown” expands from a depiction of the ills of health care into a sweeping critique of late-stage capitalism. The winners and finalists of the 2023 Pulitzer Prizes were announced on May 8, including 19 literary honorees. The “breakdown” mentioned in the book’s title refers not to James or Lunden but to America, a nation that Lunden argues has been ailing for a long time. The interwoven relationship between two women facing illness and treatment across centuries becomes the frame for an ambitious and deeply researched examination and contextualization of medicine and health care in the United States. Though memoir plays a crucial role in Lunden’s story, “American Breakdown” is ultimately not a memoir. As Lunden puts it: “A network of entwined lives, theories, and treatment advances runs from Alice and William in the late nineteenth century” to her arrival at her doctor’s office in the late 20th century. Sister to more famous brothers, the writer Henry and the psychologist William, Alice serves as a fitting historical and literary reference point for the chronically ill and variously diagnosed, including Lunden. Intriguingly, “American Breakdown” begins not with Lunden’s story but rather with the 19th-century woman of the book’s subtitle, diarist Alice James. |
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